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ethics                                                          

Determination of death
Acceptance of organ procurement and transplantation depends, in large part on public confidence that cadaver organs including livers are being taken from people who are truly dead in the public's understanding of that term and not as one pundit joked Kind of dead . In other words the often-quoted truism that the determination of death is a medical decision hides the reality that the concept of death while given both a medical and legal rationale, is fundamentally a social concept informed by cultural and religious beliefs, not a scientific concept.
There have been efforts to broaden the category of what constitutes death in humans including suggestions that infants with anencephaly and persons in persistent vegetative states be treated as though dead for purposes of organ donation. These efforts have met with significant public and professional resistance. There are two opposing schools of thought from those who are unhappy with the current definition of death for transplant

procurement purposes :
Those who believe that the current whole brain death criteria should be narrowed to require stricter criteria, prolonged absolution and more mandatory neurological testing and
Those who believe that the criteria should be widened to include patients who have been declared dead by traditional cardiopulmonary criteria or who are by current criteria alive but have been diagnosed with 'permanent loss of consciousness'

Altruism Vs Duty or Payment for Organs
Living donors are usually classified into three categories:
1. Living Related Donors (such as parents, siblings or children) who are genetically related to the recipients.
2. Living Emotionally Related Donors (Such as spouses, significant others and close friends) who are genetically unrelated.
3. Living Unrelated Donors who are strangers to the recipient and who may or may not be compensated for their donated organ (not recommended anytime).

Organ donation by living donors brings in focus perplexing ethical problems because of the dangers of coercion and external as well as self-generated pressures on the donor. Although wishing to respect the freely made decisions of prospective donors with decision making capacity and valuing the life-saving potential of this gift to the recipients and the satisfaction of donors, liver transplantation teams have been forced to evaluate the motives, the capacities and feelings of prospective donors in a variety of factual contexts.

Anencephalic and xenograft organs
Human organ transplants using anencephalic and xenograft organ donors are not a common practice in India.


Selection of patients for transplantation
nursing

Equitable selection and access
The system of distribution of cadaver livers is theoretically blind to the possibility of discrimination based on age, race, gender and socio-economic status. In practice, this equity has not always proved to be the case and unanticipated distortions in the allocation of donor organs made. Competition between large and small transplantation programmes purportedly deprive the neediest end stage liver disease patients of available organs of the special relationships between certain hospitals and organ procurement agencies that lead to organs going to specific hospitals rather than patients with greatest priority. These contribution issues do not instill a public sense of fairness about the organ allocation process. Age has also become a contentious issue; Some argue that liver transplantation patients older than 60 years do as well as younger patients and should not be excluded solely on the grounds of age whereas others argue in this youth oriented society, organs should go to the young on the basis of future productivity rather than to older candidates on the basis of future productivity.
Patients with end stage alcoholic disease (Cirrhosis)
Adding to the stigma of alcoholism have been the medical arguments of
1. Typical Multiple organ damage and severe malnutrition that could complicate the patient's ability to withstand long surgical procedure and post operative care.
2. The prospect of patient's non-compliance with the lifelong immune-suppressive regimen in a manner (i.e. a return to alcohol) leading to a rejection of the transplanted organ.

Re-transplantation
As a generalization, one can observe a serious difference in perception of ethical duties towards specific patients on the part of transplantation surgeons and other team members compared with non- transplantation team professionals. Transplantation surgeons in particular almost invariably feel a greater duty towards patients on whom they have already operated in contrast to patients who have been accepted for transplantation and are awaiting their first organ despite the fact that technically all are their patients, at least in terms of the transplantation programmes in which they are involved or lead. This is particularly true in the case of paediatric patients. For this reason, the issue of re-transplantation can become extremely controversial for some and totally routine for others, even if the patient's lives hang in the balance.If donor livers are scarce and re-transplantation of one patient is chosen over primary transplantation of another, the latter might die on the waiting list and the issue of fairness or equity becomes irrelevant.

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